After a degree in Biochemical Sciences (1987), Carine Munaut obtained her Doctoral thesis in Biomedical Sciences under the supervision of Professor Jean-Michel Foidart. To complete her training in molecular biology, Carine Munaut stayed a little over two years at the Biochemical Laboratory of Professor Karl Tryggvason (Oulu, Finland). Over the course of her thesis work Carine Munaut was interested in the physio-pathological remodelling of the extracellular matrix. A qualified FRS-FNRS researcher (2000) her current research is carried out at the Biology of Tumours and Development Laboratory, GIGA-R, jointly directed by Professors Agnès Noël and Jean-Michel Foidart.

Selection of publications

Munaut C, Boniver J, Foidart J-M, Deprez M. Macrophage migration inhibiting factor (MIF) expression in human glioblastomas correlates with VEGF expression. Neuropathol Appl Neurobiol, 2002, 28, 452-460

Munaut C, Noel A, Hougrand O, Foidart J-M, Boniver J, Deprez M. Vascular endothelial growth factor expression correlates with metalloproteinases MT1-MMP, MMP-2 and MMP-9 in human glioblastomas. Int J Cancer 2003, 106, 848-55

Munaut C, Lorquet S, Pèqueux C, Blacher S, Berndt S, Frankenne F, Foidart J-M. Hypoxia is responsible for soluble vascular endothelial growth factor but not for soluble endoglin induction in villous trophoblast. Hum. Reprod. 2008, 23, 1407-1415.

Dos Santos Mendes S, Candi A., Vansteenbrugge M, Pignon MR, Bult H, Boudjeltia KZ, Munaut C, Raes M. Microarray analyses of the effects of NF-kappaB or PI3K pathway inhibitors on the LPS-induced gene expression profile in RAW264.7 cells: synergistic effects of rapamycin on LPS-induced MMP9-overexpression. Cell Signal 2009, 21, 1109-1122.

Piette C, Deprez M, Foidart JM, Noel A., Munaut C. The dexamethasone-induced inhibition of proliferation, migration and invasion in glioma cell lines is antagonized by MIFand can be enhanced by specific MIF inhibitors. J Biol Chem 2009,284: 32483-32492